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Fragment Crystallizable (Fc)-Free Certolizumab Pegol is not Bound by Rheumatoid Factors, while Fc Containing Biological DMARDs Are, Driving Immune Complex Formation and Cellular Clearance

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CIMZIA® is associated with a BOXED WARNING regarding serious infections and malignancy and important WARNINGS AND PRECAUTIONS, including heart failure, anaphylaxis, or serious allergic reactions, hepatitis B virus reaction, demyelinating disease, cytopenius, or pancytopenia, and Lupus-like syndrome.

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