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UCB Medicines: Clinical Studies and Scientific Research Publication

Publications

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This page contains links to basic science and clinical research published on UCB medicines and disease areas of focus. The information is limited to products that have been approved for use by the U.S. Food and Drug Administration (FDA) and may contain information that is not part of the FDA-approved Prescribing Information (eg, doses, uses, devices, populations). UCB, Inc. does not recommend or endorse the use of its products in a manner not consistent with the approved Prescribing Information. Please see the Full Prescribing Information for each product when making clinical decisions.

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Phase:
pre clinical

RYSTIGGO® (rozanolixizumab-noli)

Generalized Myasthenia
Gravis

Generation and characterization of a high affinity anti-human FcRn antibody, rozanolixizumab, and the effects of different molecular formats on the reduction of plasma IgG concentration

Smith Bryan, Kiessling Andrea, Lledo-Garcia Rocio et al.  October 01, 2024
phase 3

ZILBRYSQ® (zilucoplan)

Generalized Myasthenia
Gravis

Maintenance of zilucoplan efficacy in patients with generalised myasthenia gravis up to 24 weeks: a model-informed analysis

Guillemette de la Borderie, Chimits Damien, Boroojerdi Babak et al.  September 21, 2024
phase 3

RYSTIGGO® (rozanolixizumab-noli)

Generalized Myasthenia
Gravis

Efficacy and safety of rozanolixizumab in patients with muscle-specific tyrosine kinase autoantibody-positive generalised myasthenia gravis: a subgroup analysis of the randomised, double-blind, placebo-controlled, adaptive phase III MycarinG study

Habib A. Ali, Sacconi Sabrina, Giovanni Antonini et al.  September 12, 2024
phase 3

BIMZELX® (bimekizumab-bkzx)

Ankylosing Spondylitis, Non-radiographic Axial Spondyloarthritis

The Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-Fatigue) scale in patients with axial spondyloarthritis: psychometric properties and clinically meaningful thresholds for interpretation

David Cella, Christine de la Loge, Fatoumata Fofana et al.  August 12, 2024
phase 3

BIMZELX® (bimekizumab-bkzx)

Psoriatic Arthritis

Comparative Effectiveness of Bimekizumab and Ustekinumab in Patients with Psoriatic Arthritis at 52 Weeks Assessed Using a Matching-Adjusted Indirect Comparison

Philip J Mease, Richard B Warren, Nash Peter et al.  August 09, 2024
phase 3

BIMZELX® (bimekizumab-bkzx)

Psoriatic Arthritis

Efficacy and Safety of Bimekizumab in Patients With Psoriatic Arthritis With or Without Methotrexate: 52-Week Results From Two Phase 3 Studies

Iain B McInnes, Philip J Mease, Yoshiya Tanaka et al.  July 30, 2024
phase 2

BIMZELX® (bimekizumab-bkzx)

Ankylosing Spondylitis, Non-radiographic Axial Spondyloarthritis

Low uveitis rates in patients with axial spondyloarthritis treated with bimekizumab: pooled results from phase 2b/3 trials

Brown A. Matthew, Rudwaleit Martin, Floris Alexander van Gaalen et al.  July 08, 2024
phase 3

BIMZELX® (bimekizumab-bkzx)

Ankylosing Spondylitis, Non-radiographic Axial Spondyloarthritis

Matching-Adjusted Indirect Comparison of the 52-Week Efficacy of Bimekizumab Versus Secukinumab and Ixekizumab for the Treatment of Radiographic Axial Spondyloarthritis

Maksymowych P. Walter, Howard Thom , Mørup Michael Frank et al.  June 25, 2024
phase 3

BIMZELX® (bimekizumab-bkzx)

Hidradenitis Suppurativa

Efficacy and safety of Bimekizumab in patients with moderate-to-severe hidradenitis suppurativa (BE HEARD I and BE HEARD II):  two 48-week, randomized, double-blind, placebo-controlled, multicenter phase 3 trials.

Alexa B Kimball, Gregor B E Jemec, Christopher J Sayed et al.  June 08, 2024
phase 3

BIMZELX® (bimekizumab-bkzx)

Ankylosing Spondylitis, Non-radiographic Axial Spondyloarthritis

Improved physical functioning, sleep, work productivity and overall health-related quality of life with bimekizumab in patients with axial spondyloarthritis: results from two phase 3 studies

Dubreuil Maureen, Navarro-Compán Victoria, Boonen Annelies et al.  June 04, 2024