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UCB Medicines: Clinical Studies and Scientific Research Publication

Publications

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This page contains links to basic science and clinical research published on UCB medicines and disease areas of focus. The information is limited to products that have been approved for use by the U.S. Food and Drug Administration (FDA) and may contain information that is not part of the FDA-approved Prescribing Information (eg, doses, uses, devices, populations). UCB, Inc. does not recommend or endorse the use of its products in a manner not consistent with the approved Prescribing Information. Please see the Full Prescribing Information for each product when making clinical decisions.

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Phase:

*Includes seizure clusters and acute or prolonged seizures

137 result(s)

phase 1

BIMZELX® (bimekizumab-bkzx)

Psoriatic Arthritis

Dual IL-17A and IL-17F neutralisation by bimekizumab in psoriatic arthritis: evidence from preclinical experiments and a randomised placebo-controlled clinical trial that IL-17F contributes to human chronic tissue inflammation 

Glatt Sophie, Baeten Dominique, Terry Baker et al.  December 23, 2017
phase 1

RYSTIGGO® (rozanolixizumab-noli)

Generalized Myasthenia Gravis

The FcRn inhibitor rozanolixizumab reduces human serum IgG concentration: A randomized phase 1 study

Kiessling Peter, Lledo-Garcia Rocio, Watanabe Shikiko et al.  November 01, 2017
phase 4

CIMZIA® (certolizumab pegol)

Women's Health

Lack of placental transfer of certolizumab pegol during pregnancy: results from CRIB, a prospective, postmarketing, pharmacokinetic study. 

Mariette X, Förger F, Abraham B et al.  October 13, 2017
phase 4

CIMZIA® (certolizumab pegol)

Women's Health

Minimal to no transfer of certolizumab pegol into breast milk: results from CRADLE, a prospective, postmarketing, multicentre, pharmacokinetic study. 

Clowse ME, Förger F, Hwang C et al.  August 16, 2017
phase 3

CIMZIA® (certolizumab pegol)

Ankylosing Spondylitis, Non-radiographic Axial Spondyloarthritis

Effect of certolizumab pegol over 96 weeks of treatment on inflammation of the spine and sacroiliac joints, as measured by MRI, and the association between clinical and MRI outcomes in patients with axial spondyloarthritis. 

Braun J, Baraliakos X, Hermann et al.  April 24, 2017
phase 3

BRIVIACT® (brivaracetam) CV

Focal Onset Seizures

Efficacy and tolerability of adjunctive brivaracetam in patients with prior antiepileptic drug exposure: a post-hoc study

Ali A Asadi-Pooya, Michael R Sperling, Steve Chung et al.  February 27, 2017
phase 1

BIMZELX® (bimekizumab-bkzx)

Plaque Psoriasis

First‐in‐human randomized study of bimekizumab, a humanized monoclonal antibody and selective dual inhibitor of IL‐17A and IL‐17F, in mild psoriasis.

Glatt Sophie, Helmer Eric, Hopson Sari et al.  January 10, 2017
phase 3

BRIVIACT® (brivaracetam) CV

Focal Onset Seizures

Time to onset of sustained ≥50% responder status in patients with focal (partial-onset) seizures in three phase 3 studies of adjunctive brivaracetam treatment

Pavel Klein, Martin E Johnson, Jimmy Schiemann et al.  December 18, 2016
phase 4

CIMZIA® (certolizumab pegol)

Rheumatoid Arthritis

Head-to-head comparison of certolizumab pegol versus adalimumab in rheumatoid arthritis: 2-year efficacy and safety results from the randomised EXXELERATE study. 

Smolen JS, Burmester GR, Combe B et al.  November 15, 2016
phase 3

BRIVIACT® (brivaracetam) CV

Focal Onset Seizures

Efficacy, safety, and tolerability of adjunctive brivaracetam for secondarily generalized tonic-clonic seizures: pooled results from three phase 3 studies

Brian D Moseley, Michael R Sperling, Ali A Asadi-Pooya et al.  September 03, 2016