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UCB Medicines: Clinical Studies and Scientific Research Publication

Publications

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This page contains links to basic science and clinical research published on UCB medicines and disease areas of focus. The information is limited to products that have been approved for use by the U.S. Food and Drug Administration (FDA) and may contain information that is not part of the FDA-approved Prescribing Information (eg, doses, uses, devices, populations). UCB, Inc. does not recommend or endorse the use of its products in a manner not consistent with the approved Prescribing Information. Please see the Full Prescribing Information for each product when making clinical decisions.

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*Includes seizure clusters and acute or prolonged seizures

137 result(s)

phase 3

CIMZIA® (certolizumab pegol)

Rheumatoid Arthritis

Twenty-eight-week results from the REALISTIC phase IIIb randomized trial: efficacy, safety and predictability of response to certolizumab pegol in a diverse rheumatoid arthritis population. 

Weinblatt ME, Fleischmann R, van Vollenhoven RF et al.  November 15, 2015
phase 3

BRIVIACT® (brivaracetam) CV

Focal Onset Seizures

A randomized, double-blind, placebo-controlled, multicenter, parallel-group study to evaluate the efficacy and safety of adjunctive brivaracetam in adult patients with uncontrolled partial-onset seizures

Pavel Klein, Jimmy Schiemann, Michael R Sperling et al.  October 16, 2015
phase 3

BRIVIACT® (brivaracetam) CV

Focal Onset Seizures

An open-label, prospective, exploratory study of patients with epilepsy switching from levetiracetam to brivaracetam

Stephen L Yates, Toufic Fakhoury, Wei Liang et al.  September 29, 2015
phase 1

NAYZILAM® (midazolam) CIV

Seizure Emergencies

Pharmacokinetics, pharmacodynamics, and safety of USL261, a midazolam formulation optimized for intranasal delivery, in a randomized study with healthy volunteers.

Lindy L Bancke, Heather A Dworak, Keith A Rodvold et al.  September 02, 2015
phase 3

CIMZIA® (certolizumab pegol)

Psoriatic Arthritis

Effect of certolizumab pegol over 96 weeks in patients with psoriatic arthritis with and without prior antitumor necrosis factor exposure. 

Mease P, Deodhar A, Fleischmann R et al.  June 25, 2015
pre clinical

FINTEPLA® (fenfluramine)

Dravet Syndrome

Pharmacological characterization of an antisense knockdown zebrafish model of Dravet syndrome: inhibition of epileptic seizures by the serotonin agonist fenfluramine

Yifan Zhang, Angéla Kecskés, Daniëlle Copmans et al.  May 12, 2015
phase 3

CIMZIA® (certolizumab pegol)

Ankylosing Spondylitis, Non-radiographic Axial Spondyloarthritis

Effect of certolizumab pegol over ninety-six weeks in patients with axial spondyloarthritis. 

Sieper J, Landewe R, Rudwaleit M et al.  March 01, 2015
phase 3

CIMZIA® (certolizumab pegol)

Rheumatoid Arthritis

Two dosing regimens of certolizumab pegol in patients with active rheumatoid arthritis. 

Furst DE, Shaikh SA, Greenwald M et al.  February 01, 2015
phase 3

CIMZIA® (certolizumab pegol)

Crohn's Disease

Long-term safety and efficacy of certolizumab pegol in the treatment of Crohn’s disease: 7-year results from the PRECiSE 3 study. 

Sandborn WJ, Lee SD, Randall C et al.  August 22, 2014
phase 4

CIMZIA® (certolizumab pegol)

Rheumatoid Arthritis

Rheumatoid arthritis secondary nonresponders to TNF can attain an efficacious and safe response by switching to certolizumab pegol: a phase IV, randomised, multicentre, double-blind, 12-week study, followed by a 12-week open-label phase. 

Schiff MH, von Kempis J, Goldblum R et al.  June 27, 2014