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UCB Medicines: Clinical Studies and Scientific Research Publication

Publications

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This page contains links to basic science and clinical research published on UCB medicines and disease areas of focus. The information is limited to products that have been approved for use by the U.S. Food and Drug Administration (FDA) and may contain information that is not part of the FDA-approved Prescribing Information (eg, doses, uses, devices, populations). UCB, Inc. does not recommend or endorse the use of its products in a manner not consistent with the approved Prescribing Information. Please see the Full Prescribing Information for each product when making clinical decisions.

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Phase:
phase 3

BIMZELX® (bimekizumab-bkzx)

Psoriatic Arthritis

Comparative Effectiveness of Bimekizumab in Psoriatic Arthritis: A Model-Based Meta-Analysis of American College of Rheumatology Response Criteria

Alan Maloney, Pinky Dua, Ghada F. Ahmed et al.  December 10, 2023
phase 3

BIMZELX® (bimekizumab-bkzx)

Ankylosing Spondylitis, Non-radiographic Axial Spondyloarthritis

Work productivity in patients with axial spondyloarthritis initiating biological or targeted synthetic disease-modifying antirheumatic drugs: a systematic literature review and meta-analysis

Rudwaleit Martin, Mørup Michael Frank, Brittany Humphries et al.  November 30, 2023
phase 3

BIMZELX® (bimekizumab-bkzx)

Ankylosing Spondylitis, Non-radiographic Axial Spondyloarthritis

Comparative efficacy and safety of bimekizumab in axial spondyloarthritis: a systematic literature review and network meta-analysis.    

Deodhar Atul, Machado M. Pedro, Mørup Michael Frank et al.  November 08, 2023
phase 4

BIMZELX® (bimekizumab-bkzx)

Psoriatic Arthritis

Safe and Effective Subcutaneous Self-Injection of Bimekizumab with Safety Syringe and Auto-Injector Devices: Results from a Multicenter, Randomized, Open-Label Study in Patients with Psoriatic Arthritis.   

Kivitz J. Alan, Ellis M. Alicia, Vishvesh Shende et al.  October 03, 2023
phase 3

BIMZELX® (bimekizumab-bkzx)

Psoriatic Arthritis

Cost-effectiveness analysis of bimekizumab for the treatment of active psoriatic arthritis in Sweden 

Valgerdur Sigurdardottir, Anna Engstrom, Patric Berling et al.  September 15, 2023
phase 3

BIMZELX® (bimekizumab-bkzx)

Psoriatic Arthritis

Bimekizumab treatment in biologic DMARD-naïve patients with active psoriatic arthritis: 52-week efficacy and safety results from the phase 3, randomised, placebocontrolled, active reference BE OPTIMAL study

Christopher T Ritchlin, Coates C. Laura, McInnes B. Iain et al.  September 11, 2023
pre clinical

ZILBRYSQ® (zilucoplan)

Generalized Myasthenia
Gravis

Zilucoplan, a macrocyclic peptide inhibitor of human complement component 5, uses a dual mode of action to prevent terminal complement pathway activation

Tang Guo-Qing, Tang Yalan, Dhamnaskar Ketki et al.  August 09, 2023
phase 3

BIMZELX® (bimekizumab-bkzx)

Ankylosing Spondylitis, Non-radiographic Axial Spondyloarthritis

Correction: Efficacy and safety of bimekizumab in axial spondyloarthritis: results of two parallel phase 3 randomised controlled trials 

van der Heijde D, Deodhar Atul, Xenofon Baraliakos et al.  July 03, 2023
phase 3

BIMZELX® (bimekizumab-bkzx)

Plaque Psoriasis

Bimekizumab efficacy and safety in patients with moderate to severe plaque psoriasis:  Two-year interim results form the open-label extension of the randomized BE RADIANT phase 3b trial.

Strober Bruce, Paul Carle, Blauvelt Andrew et al.  May 12, 2023
phase 3

ZILBRYSQ® (zilucoplan)

Generalized Myasthenia
Gravis

Safety and efficacy of zilucoplan in patients with generalised myasthenia gravis (RAISE): a randomised, double-blind, placebo-controlled, phase 3 study

James F Howard Jr, Bresch Saskia, Genge Angela et al.  May 01, 2023