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UCB Medicines: Clinical Studies and Scientific Research Publication

Publications

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This page contains links to basic science and clinical research published on UCB medicines and disease areas of focus. The information is limited to products that have been approved for use by the U.S. Food and Drug Administration (FDA) and may contain information that is not part of the FDA-approved Prescribing Information (eg, doses, uses, devices, populations). UCB, Inc. does not recommend or endorse the use of its products in a manner not consistent with the approved Prescribing Information. Please see the Full Prescribing Information for each product when making clinical decisions.

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*Includes seizure clusters and acute or prolonged seizures

137 result(s)

phase 3

NAYZILAM® (midazolam) CIV

Seizure Emergencies

Return to full baseline functionality after repeated intermittent use of midazolam nasal spray in patients with seizure clusters: post hoc analysis of an open-label extension trial

Kamil Detyniecki, Marcus Brunnert, Rita Campos et al.  October 29, 2023
phase 4

BIMZELX® (bimekizumab-bkzx)

Psoriatic Arthritis

Safe and Effective Subcutaneous Self-Injection of Bimekizumab with Safety Syringe and Auto-Injector Devices: Results from a Multicenter, Randomized, Open-Label Study in Patients with Psoriatic Arthritis.   

Kivitz J. Alan, Ellis M. Alicia, Vishvesh Shende et al.  October 03, 2023
phase 3

BIMZELX® (bimekizumab-bkzx)

Psoriatic Arthritis

Cost-effectiveness analysis of bimekizumab for the treatment of active psoriatic arthritis in Sweden 

Valgerdur Sigurdardottir, Anna Engstrom, Patric Berling et al.  September 15, 2023
phase 3

BIMZELX® (bimekizumab-bkzx)

Psoriatic Arthritis

Bimekizumab treatment in biologic DMARD-naïve patients with active psoriatic arthritis: 52-week efficacy and safety results from the phase 3, randomised, placebocontrolled, active reference BE OPTIMAL study

Christopher T Ritchlin, Coates C. Laura, McInnes B. Iain et al.  September 11, 2023
phase 4

BRIVIACT® (brivaracetam) CV

Focal Onset Seizures

Effectiveness and tolerability of 12-month brivaracetam in the real world: EXPERIENCE, an international pooled analysis of individual patient records 

Vicente Villanueva, Cédric Laloyaux, Wendyl D'Souza et al.  September 09, 2023
phase 3

BRIVIACT® (brivaracetam) CV

Focal Onset Seizures

Long-term safety and efficacy of adjunctive brivaracetam in pediatric patients with epilepsy: an open-label, follow-up trial

Lieven Lagae, Kerstin Alexandra Klotz, András Fogarasi et al.  September 05, 2023
phase 3

FINTEPLA® (fenfluramine)

Dravet Syndrome

Fenfluramine in the treatment of Dravet syndrome: results of a third randomized, placebo-controlled clinical trial

Joseph Sullivan, Lieven Lagae, J Helen Cross et al.  August 17, 2023
pre clinical

ZILBRYSQ® (zilucoplan)

Generalized Myasthenia Gravis

Zilucoplan, a macrocyclic peptide inhibitor of human complement component 5, uses a dual mode of action to prevent terminal complement pathway activation

Tang Guo-Qing, Tang Yalan, Dhamnaskar Ketki et al.  August 09, 2023
phase 3

BIMZELX® (bimekizumab-bkzx)

Ankylosing Spondylitis, Non-radiographic Axial Spondyloarthritis

Correction: Efficacy and safety of bimekizumab in axial spondyloarthritis: results of two parallel phase 3 randomised controlled trials 

van der Heijde D, Deodhar Atul, Xenofon Baraliakos et al.  July 03, 2023
pre clinical

FINTEPLA® (fenfluramine)

Dravet Syndrome, Lennox-Gastaut Syndrome

Fenfluramine: a plethora of mechanisms?

Jo Sourbron, Lieven Lagae et al.  May 12, 2023