UCB Medicines: Clinical Studies and Scientific Research Publication
Publications
CIMZIA® (certolizumab pegol)
Limited radiographic progression and sustained reductions in MRI inflammation in patients with axial spondyloarthritis: 4-year imaging outcomes from the RAPID-axSpA phase III randomised trial.
BIMZELX® (bimekizumab-bkzx)
Dual IL-17A and IL-17F neutralisation by bimekizumab in psoriatic arthritis: evidence from preclinical experiments and a randomised placebo-controlled clinical trial that IL-17F contributes to human chronic tissue inflammation
RYSTIGGO® (rozanolixizumab-noli)
The FcRn inhibitor rozanolixizumab reduces human serum IgG concentration: A randomized phase 1 study
CIMZIA® (certolizumab pegol)
Lack of placental transfer of certolizumab pegol during pregnancy: results from CRIB, a prospective, postmarketing, pharmacokinetic study.
CIMZIA® (certolizumab pegol)
Minimal to no transfer of certolizumab pegol into breast milk: results from CRADLE, a prospective, postmarketing, multicentre, pharmacokinetic study.
CIMZIA® (certolizumab pegol)
Effect of certolizumab pegol over 96 weeks of treatment on inflammation of the spine and sacroiliac joints, as measured by MRI, and the association between clinical and MRI outcomes in patients with axial spondyloarthritis.
BIMZELX® (bimekizumab-bkzx)
First‐in‐human randomized study of bimekizumab, a humanized monoclonal antibody and selective dual inhibitor of IL‐17A and IL‐17F, in mild psoriasis.
CIMZIA® (certolizumab pegol)
Head-to-head comparison of certolizumab pegol versus adalimumab in rheumatoid arthritis: 2-year efficacy and safety results from the randomised EXXELERATE study.
CIMZIA® (certolizumab pegol)
Reinduction with certolizumab pegol in patients with Crohn’s disease experiencing disease exacerbation: 7-year data from the PRECiSE 4 study.
CIMZIA® (certolizumab pegol)
Safety of long-term treatment with certolizumab pegol in patients with Crohn’s disease, based on a pooled analysis of data from clinical trials.