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UCB Medicines: Clinical Studies and Scientific Research Publication

Publications

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This page contains links to basic science and clinical research published on UCB medicines and disease areas of focus. The information is limited to products that have been approved for use by the U.S. Food and Drug Administration (FDA) and may contain information that is not part of the FDA-approved Prescribing Information (eg, doses, uses, devices, populations). UCB, Inc. does not recommend or endorse the use of its products in a manner not consistent with the approved Prescribing Information. Please see the Full Prescribing Information for each product when making clinical decisions.

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*Includes seizure clusters and acute or prolonged seizures

137 result(s)

phase 2

BIMZELX® (bimekizumab-bkzx)

Plaque Psoriasis

Bimekizumab for patients with moderate to severe plaque psoriasis: 60-week results from BE ABLE 2, a randomized, double-blinded, placebo-controlled, phase 2b extension study.

Blauvelt Andrew, Krueger James, Feldman Steven et al.  May 29, 2020
phase 3

BRIVIACT® (brivaracetam) CV

Focal Onset Seizures

Effect of lifetime antiepileptic drug treatment history on efficacy and tolerability of adjunctive brivaracetam in adults with focal seizures: post-hoc analysis of a randomized, placebo-controlled trial

Pavel Klein, Richard McLachlan, Kathy Foris et al.  May 25, 2020
phase 2

ZILBRYSQ® (zilucoplan)

Generalized Myasthenia Gravis

Clinical Effects of the Self-administered Subcutaneous Complement Inhibitor Zilucoplan in Patients With Moderate to Severe Generalized Myasthenia Gravis: Results of a Phase 2 Randomized, Double-Blind, Placebo-Controlled, Multicenter Clinical Trial

James F Howard Jr, Nowak J Richard, Wolfe I Gil et al.  May 01, 2020
phase 2

BIMZELX® (bimekizumab-bkzx)

Ankylosing Spondylitis, Non-radiographic Axial Spondyloarthritis

Dual neutralisation of interleukin-17A and interleukin-17F with bimekizumab in patients with active ankylosing spondylitis: results from a 48-week phase IIb, randomised, double-blind, placebo-controlled, dose-ranging study 

Desiree van der Heijde, Gensler S. Lianne, Deodhar Atul et al.  April 06, 2020
phase 2

BIMZELX® (bimekizumab-bkzx)

Psoriatic Arthritis

Bimekizumab in patients with active psoriatic arthritis: results from a 48-week, randomised, double-blind, placebo-controlled, dose-ranging phase 2b trial

Christopher T Ritchlin, Kavanaugh Arthur, Joseph F Merola et al.  February 08, 2020
phase 3

FINTEPLA® (fenfluramine)

Dravet Syndrome

Fenfluramine hydrochloride for the treatment of seizures in Dravet syndrome: a randomised, double-blind, placebo-controlled trial

Lieven Lagae, Joseph Sullivan, Kelly Knupp et al.  December 17, 2019
phase 3

FINTEPLA® (fenfluramine)

Dravet Syndrome

Fenfluramine for treatment-resistant seizures in patients with Dravet syndrome receiving stiripentol-inclusive regimens: a randomized clinical trial

Rima Nabbout, Arun Mistry, Sameer Zuberi et al.  December 02, 2019
phase 3

NAYZILAM® (midazolam) CIV

Seizure Emergencies

Safety and efficacy of midazolam nasal spray in the outpatient treatment of patients with seizure clusters: an open-label extension trial

James W Wheless, Tze-Chiang Meng, Peter J Van Ess et al.  July 29, 2019
phase 2

BRIVIACT® (brivaracetam) CV

Focal Onset Seizures

Safety and tolerability of adjunctive brivaracetam in pediatric patients <16 years with epilepsy: an open-label trial

Edwin Liu, Deanne Dilley, Belinda McDonough et al.  June 28, 2019
phase 3

NAYZILAM® (midazolam) CIV

Seizure Emergencies

Safety and efficacy of midazolam nasal spray in the outpatient treatment of patients with seizure clusters - a randomized, double-blind, placebo-controlled trial

Kamil Detyniecki, Peter J Van Ess, David J Sequeira et al.  May 29, 2019